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Role of Amino-Terminal Domain in the Assembly Mechanism of Kainate-Subtype Glutamate Receptor Ion Channels

✍ Scribed by Chittori, Sagar; Kumar, Janesh; Lomash, Suvendu; Zhao, Huaying; Schuck, Peter; Mayer, Mark L.

Book ID
123287946
Publisher
Biophysical Society
Year
2014
Tongue
English
Weight
41 KB
Volume
106
Category
Article
ISSN
0006-3495

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Background: Aquaporin-1 (AQP1) functions as an osmotic water channel and a gated cation channel. Activation of the AQP1 ion conductance by intracellular cGMP was hypothesized to involve the carboxyl (C-) terminus, based on amino acid sequence alignments with cyclicnucleotide-gated channels and cGMP-