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Role of Akt/protein kinase B in the activity of transcriptional coactivator p300

✍ Scribed by J. Chen; S. S. Halappanavar; J. R. St-Germain; B. K. Tsang; Q. Li

Book ID
105757857
Publisher
Springer
Year
2004
Tongue
English
Weight
406 KB
Volume
61
Category
Article
ISSN
1420-682X

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## Abstract Liver fibrosis is a common consequence of various chronic liver injuries, including virus infection and ethanol. Activated hepatic stellate cells (HSCs) contribute to liver fibrosis through the accumulation of extracellular matrix proteins, including type I alpha collagen (COL1A). The a