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Role of a proteolysis-inducing factor (PIF) in cachexia induced by a human melanoma (G361)

✍ Scribed by Todorov, P T; Field, W N; Tisdale, M J


Book ID
110002377
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
94 KB
Volume
80
Category
Article
ISSN
0007-0920

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Cachexia often causes deterioration in the quality of life in cancer patients; however, its mechanism remains poorly understood. Cachexia has often been observed in experimental animals with bone metastases, and parathyroid hormonerelated protein (PTHrP) plays an important role in the formation of s