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Role of a new member of IGFBP superfamily, IGFBP-rP10, in proliferation and differentiation of osteoblastic cells

✍ Scribed by Yasuaki Shibata; Tomoo Tsukazaki; Kazunari Hirata; Cheng Xin; Akira Yamaguchi


Book ID
116289497
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
575 KB
Volume
325
Category
Article
ISSN
0006-291X

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## Abstract Both transforming growth factor (TGF‐β) and growth and development factor (GDF)‐8 (myostatin) affect muscle differentiation by suppressing proliferation and differentiation of myogenic cells. In contrast, insulin‐like growth factors (IGFs) stimulate both proliferation and differentiatio