Role of 1,25-dihydroxyvitamin D on the skeletal resistance to parathyroid hormone
โ Scribed by Galceran, Tilde; Martin, Kevin J; Morrissey, Jeremiah J; Slatopolsky, Eduardo
- Book ID
- 109880922
- Publisher
- Nature Publishing Group
- Year
- 1987
- Tongue
- English
- Weight
- 599 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0085-2538
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๐ SIMILAR VOLUMES
Calcium absorption declines with age. Because 1,25-dihydroxyvitamin D (1,25(OH),D) is the major hormone controlling calcium absorption, changes in vitamin D metabolism may account for the malabsorption of aging. Serum levels of 1,25(OH),D have been reported to either decrease or remain unchanged wit
## Abstract The 25โhydroxyvitamin D~3~โ24โhydroxylase mRNA is tightly and reciprocally regulated by 1,25โdihydroxyvitamin D~3~ (1,25(OH)~2~D~3~) and parathyroid hormone (PTH). The upregulation of the 24โhydroxylase by 1,25(OH)~2~D~3~ is well established and occurs at the transcriptional level throu