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Role of 0(6)-alkylguanine DNA alkyltransferase in the implementation of the antitumor activity of N-nitrosoureas (a review)

✍ Scribed by L. B. Gorbacheva; G. V. Kukushkina


Book ID
112396932
Publisher
Springer
Year
1989
Tongue
English
Weight
660 KB
Volume
23
Category
Article
ISSN
0091-150X

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O 6 -Alkylguanine-DNA alkyltransferase (AGT) is re-group (14/31) was twice that in the group treated sponsible for repairing the O 6 -alkylguanine lesion with ENU alone, consistent with the loss of AGT in DNA. There is wide variation in the levels of AGT activity in these cells. There was no strand