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Role for the double-stranded RNA activated protein kinase PKR in E2F-1-induced apoptosis

✍ Scribed by Vorburger, Stephan A; Pataer, Abujiang; Yoshida, Kazumi; Barber, Glen N; Xia, Weiya; Chiao, Paul; Ellis, Lee M; Hung, Mien-Chie; Swisher, Stephen G; Hunt, Kelly K


Book ID
110066919
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
654 KB
Volume
21
Category
Article
ISSN
0950-9232

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Double-stranded RNA–activated protein ki
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PKR, the double-stranded RNA (dsRNA)-activated serine/threonine kinase, has been implicated as an important component of host responses to infection and various situations of cellular stress. The involvement of PKR in signal transduction and regulation of transcription suggested to us that it may pl