Left±right asymmetric signaling molecules in mammals include three transforming growth factor b (TGFb)-related factors, Nodal, Lefty1 and Lefty2. They are all expressed on the left half of developing mouse embryos. Nodal acts as a left-side determinant by transducing signals through Smad and FAST an
✦ LIBER ✦
Role for retinoid signaling in left–right asymmetric digestive organ morphogenesis
✍ Scribed by Kristen Lipscomb; Christopher Schmitt; Amanda Sablyak; Jeffrey A. Yoder; Nanette Nascone-Yoder
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 580 KB
- Volume
- 235
- Category
- Article
- ISSN
- 1058-8388
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## Abstract Nodal factors play crucial roles during embryogenesis of chordates. They have been implicated in a number of developmental processes, including mesoderm and endoderm formation and patterning of the embryo along the anterior–posterior and left–right axes. We have analyzed the function of