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Role for IGFBP7 in Senescence Induction by BRAF

โœ Scribed by Narendra Wajapeyee; Ryan W. Serra; Xiaochun Zhu; Meera Mahalingam; Michael R. Green


Book ID
116354366
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
65 KB
Volume
141
Category
Article
ISSN
0092-8674

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## Abstract Recently, it was shown that __MYCN__ amplified cells spontaneously expulse extrachromosomally amplified gene copies by micronuclei formation. Furthermore, it was shown that these cells lose their malignant phenotype and start to age. We tested whether it is possible to encourage neurobl