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Role for Hedgehog signaling in hepatic stellate cell activation and viability

✍ Scribed by Sicklick, Jason K; Li, Yin-Xiong; Choi, Steve S; Qi, Yi; Chen, Wei; Bustamante, Marcia; Huang, Jiawen; Zdanowicz, Marzena; Camp, Terese; Torbenson, Michael S


Book ID
109885973
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
402 KB
Volume
85
Category
Article
ISSN
0023-6837

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Hepatic stellate cells (HSCs) survive and proliferate in the chronically injured liver. ATPbinding cassette (ABC) transporters play a crucial role in cell viability by transporting toxic metabolites or xenobiotics out of the cell. ABC transporter expression in HSCs and its relevance to cell viabilit