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Role and potential for therapeutic targeting of MYB in leukemia

โœ Scribed by Pattabiraman, D R; Gonda, T J


Book ID
120344277
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
566 KB
Volume
27
Category
Article
ISSN
0887-6924

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Role and potential for therapeutic targe
โœ Pattabiraman, D R; Gonda, T J ๐Ÿ“‚ Article ๐Ÿ“… 2012 ๐Ÿ› Nature Publishing Group ๐ŸŒ English โš– 566 KB

The Myb protein was first identified as an oncogene that causes leukemia in chickens. Since then, it has been widely associated with different types of cancers and studied in detail in myeloid leukemias. However, despite these studies, its role in the induction, pathogenesis and maintenance of AML,