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Role and mode of action of DOC2 in neurotransmitter release and induction of postsynaptic long-term potentiation

✍ Scribed by Yoshimi Takai; Takuya Sasaki; Satoshi Orita; Gaku Sakaguchi; Tomoyuki Takahashi; Toshiya Manabe; Katsunori Kobayashi; Sumiko Mochida


Book ID
117364490
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
81 KB
Volume
31
Category
Article
ISSN
0168-0102

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Hippocampal long-term potentiation (LTP) is reduced in aged relative to young F-344 rats when peri-threshold stimulation protocols (several stimulus pulses at 100-200 Hz) are used. The present study was designed to examine the possibility that this LTP-induction deficit is caused by a reduced overla