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Roflumilast inhibits leukocyte-endothelial cell interactions, expression of adhesion molecules and microvascular permeability

✍ Scribed by M-J Sanz; J Cortijo; M A Taha; M Cerdá-Nicolás; E Schatton; B Burgbacher; J Klar; H Tenor; C Schudt; A C Issekutz; A Hatzelmann; E J Morcillo

Book ID
110009701
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
290 KB
Volume
152
Category
Article
ISSN
0007-1188

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The late onset of necrosis and fibrosis in normal tissues can be a serious consequence of radiotherapy in cancer patients. Because radiation-induced vascular injury precedes the tissue damage, vascular injury is regarded as crucial in the pathogenesis of tissue damage. An understanding of the proces