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Rodenticides, Comparative Toxicities of Warfarin and Some 2-Acyl-1,3-indandiones in Rats

✍ Scribed by Saunders, J. P.; Heisey, S. R.; Goldstone, A. D.; Bay, E. C.


Book ID
127329358
Publisher
American Chemical Society
Year
1955
Tongue
English
Weight
457 KB
Volume
3
Category
Article
ISSN
0021-8561

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## Abstract The developmental toxicity of the three main metabolites of __N__‐methyl‐2‐pyrrolidone (NMP) was studied in Sprague‐Dawley rats. Pregnant rats were given 5‐hydroxy‐__N__‐methyl‐2‐pyrrolidone (5‐HNMP; 0, 250, 500, 750 or 1000 mg kg^−1^ day^−1^), __N__‐methylsuccinimide (MSI; 0, 500, 750,