## Abstract Holmans' possible triangle test for affected sib pairs has proven to be a powerful tool for linkage analysis. This test is a likelihood‐ratio test for which maximization is restricted to the set of possible sharing probabilities. Here, we extend the possible triangle test to take into a
✦ LIBER ✦
Robust Multipoint Identical-by-Descent Mapping for Affected Relative Pairs
✍ Scribed by Daniel J. Schaid; Jason P. Sinnwell; Stephen N. Thibodeau
- Book ID
- 117854575
- Publisher
- American Society of Human Genetics
- Year
- 2005
- Tongue
- English
- Weight
- 382 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0002-9297
- DOI
- 10.1086/427343
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## Abstract Identification of genes involved in complex traits by traditional (lod score) linkage analysis is difficult due to many complicating factors. An unfortunate drawback of non‐parametric procedures in general, though, is their low power to detect genetic effects. Recently, Dudoit and Speed