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Robust allocation schemes for clinical trials with prognostic factors

✍ Scribed by Douglas P. Wiens


Book ID
118481154
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
333 KB
Volume
127
Category
Article
ISSN
0378-3758

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Background. Patients with advanced or metastatic cancer treated in Phase I clinical trials are considered to have a poor prognosis. Survival from first treatment in a Phase I trial was determined for 349 patients. Univariate and multivariate survival analyses were performed to determine whether pote