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RNase and alkali sensitivity of closed circular mitochondrial DNA of rat ascites hepatoma cells

✍ Scribed by Michiko Miyaki; Kazuko Koide; Tetsuo Ono


Book ID
118854044
Publisher
Elsevier Science
Year
1973
Tongue
English
Weight
386 KB
Volume
50
Category
Article
ISSN
0006-291X

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## Abstract We studied the genotoxic potential of a carcinogen in the human hepatoma cell line, HepG2 and in primary rat hepatocyte culture. HepG2 is a well differentiated human hepatoblastoma cell line with biotransforming capacity. Rat hepatocytes were obtained by the standard two‐step in situ pe