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RNAi and small interfering RNAs in human disease therapeutic applications

✍ Scribed by Monica R. Lares; John J. Rossi; Dominique L. Ouellet

Book ID
113932335
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
567 KB
Volume
28
Category
Article
ISSN
0167-7799

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RNAi and small interfering RNAs in human
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✍ Monica R. Lares; John J. Rossi; Dominique L. Ouellet πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 567 KB

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Small RNAs, including short interfering RNAs (siRNAs) and microRNAs (miRNAs), are ubiquitous, versatile repressors of gene expression in plants, animals, and many fungi. They can trigger destruction of homologous mRNA or inhibition of cognate mRNA translation and play an important role in maintainin