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RNA-templated DNA repair

✍ Scribed by Storici, Francesca; Bebenek, Katarzyna; Kunkel, Thomas A.; Gordenin, Dmitry A.; Resnick, Michael A.


Book ID
109896904
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
73 KB
Volume
448
Category
Article
ISSN
0028-0836

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## Abstract Two mechanisms are available for the repair of DNA double‐strand breaks (DSBs) in eukaryotic cells: homology directed repair (HDR) and non‐homologous end‐joining (NHEJ). While NHEJ is not restricted to a particular phase of the cell cycle, it is incapable of accurately repairing DBSs th