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RNA reprogramming and repair based on trans-splicing group I ribozymes

✍ Scribed by Tonje Fiskaa; Åsa B. Birgisdottir

Book ID
103851080
Publisher
Elsevier
Year
2010
Tongue
English
Weight
928 KB
Volume
27
Category
Article
ISSN
1871-6784

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## Abstract ## Background Group I intron‐based __trans__‐splicing ribozyme, which can specifically reprogram human telomerase reverse transcriptase (hTERT) RNA, could be a useful tool for tumor‐targeted gene therapy. In the present study, the therapeutic feasibility of this ribozyme was investigat