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RNA polymerase II C-terminal repeat influences response to transcriptional enhancer signals

โœ Scribed by Scafe, Charles; Chao, David; Lopes, John; Hirsch, Jeanne P.; Henry, Susan; Young, Richard A.


Book ID
109766058
Publisher
Nature Publishing Group
Year
1990
Tongue
English
Weight
564 KB
Volume
347
Category
Article
ISSN
0028-0836

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Cdc2 kinase triggers the entry of mammalian cells into mitosis, the only cell cycle phase in which transcription is globally repressed. We show here that Cdc2 kinase phosphorylates components of the RNA polymerase II transcription machinery including the RNA polymerase II carboxy-terminal repeat dom