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RNA interference targeting leptin gene effect on hepatic stellate cells

โœ Scribed by Xue Xiulan; Lin Jusheng; Song Yuhu; Sun Xuemei; Zhou Hejun


Book ID
105645555
Publisher
Springer-Verlag
Year
2005
Tongue
Chinese
Weight
316 KB
Volume
25
Category
Article
ISSN
0510-9752

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Although leptin induces fibrotic activity in hepatic stellate cells (HSCs), the mechanisms are not entirely understood. To investigate the potential role of reduced nicotinamide adenine dinucleotide phosphate oxidase (NADPH) and reactive oxygen species (ROS) in leptin signaling in HSCs, we analyzed