RNA Interference mediated knockdown of genes in order to increase protein production using the baculovirus expression system

In vitro and in vivo RNA interference me

In vitro and in vivo RNA interference mediated suppression of Tn-caspase-1 for improved recombinant protein production in High FiveTMcell culture with the baculovirus expression vector system

✍ Colin G. Hebert; James J. Valdes; William E. Bentley 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 374 KB 👁 2 views

## Abstract While traditional metabolic engineering generally relies on the augmentation of specific genes and pathways in order to increase the yield of target proteins, the advent of RNA interference (RNAi) as a biological tool has given metabolic engineers another tool capable of rationally alte