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RNA Interference-Mediated Inhibition of Erythropoietin Receptor Expression Suppresses Tumor Growth and Invasiveness in A2780 Human Ovarian Carcinoma Cells

โœ Scribed by Gyorgy Paragh; Suresh M. Kumar; Zsuzsa Rakosy; Soek-Choel Choi; Xiaowei Xu; Geza Acs


Book ID
117970873
Publisher
American Society for Investigative Pathology
Year
2009
Tongue
English
Weight
729 KB
Volume
174
Category
Article
ISSN
0002-9440

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## Abstract The effects of EGF and TGFโ€ฮฒ1 on the proliferation of 2 ovarian carcinoma cell lines (IGROV1 and OVCCR1) were evaluated. The cell lines were adapted to grow in a restricted serum (0.5%) medium. EGF was required for proliferation of both ovarian cell lines. Low doses of TGFโ€ฮฒ1 inhibited