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RNA interference in embryonic stem cells and the prospects for future therapies

โœ Scribed by Heidersbach, A; Gaspar-Maia, A; McManus, M T; Ramalho-Santos, M

Book ID
110039776
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
234 KB
Volume
13
Category
Article
ISSN
0969-7128

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## Abstract Summary: We examined whether suppression of Oct4 via RNA interference (RNAi) would affect embryonic stem (ES) cell lineage choice. Cells were transfected with plasmids containing an independently expressed reporter gene and an RNA polymerase type III promoter to constitutively express s