RNA Interference: Challenges and Therapeutic Opportunities

✍ Scribed by Mouldy Sioud (eds.)

• Publisher: Humana Press
• Year: 2015
• Tongue: English
• Leaves: 496
• Series: Methods in Molecular Biology 1218
• Edition: 1
• Category: Library

✦ Synopsis

RNA Interference: Challenges and Therapeutic Opportunities provides readers with recent advances in siRNA design, delivery, targeting and methods to minimize siRNA’s unwanted effects. Preclinical and clinical use of synthetic siRNAs, the roles of miRNAs in cancer and the promise of extracellular miRNAs for diagnosis are also covered in this meticulous collection, along with novel methods for identifying endogenous siRNAs and the annotation of small RNA transcriptomes. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory.

Comprehensive and cutting-edge, RNA Interference: Challenges and Therapeutic Opportunities will aid researchers, clinicians, teachers and biotechnologists interested in the power of RNA-based therapies.

✦ Table of Contents

Front Matter....Pages i-xvi
Back Matter....Pages 1-15
....Pages 17-36

✦ Subjects

Pharmacology/Toxicology; Human Genetics