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RNA interference as a therapeutic strategy for treating CNS disorders

✍ Scribed by Daniel Hoyer; Kumlesh K. Dev

Book ID
119226070
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
121 KB
Volume
3
Category
Article
ISSN
1740-6773

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## Abstract Damage to oligodendrocytes caused by glutamate release contributes to mental or physical handicap in periventricular leukomalacia, spinal cord injury, multiple sclerosis, and stroke, and has been attributed to activation of AMPA/kainate receptors. However, glutamate also activates unusu