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RNA interference against interleukin-5 attenuates airway inflammation and hyperresponsiveness in an asthma model

✍ Scribed by Shao-xing Chen; Feng-ying Huang; Guang-hong Tan; Cai-chun Wang; Yong-hao Huang; Hua Wang; Song-lin Zhou; Fan Chen; Ying-ying Lin; Jun-bao Liu

Book ID
111842532
Publisher
SP Zhejiang University Press
Year
2009
Tongue
English
Weight
157 KB
Volume
10
Category
Article
ISSN
1673-1581

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## Abstract ## Background Eosinophilia plays the major role in the pathogenesis of asthma and correlates with the up‐regulation of eotaxin, which, together with interleukin (IL)‐5, is important for differentiation, chemo‐attraction, degranulation, and survival of eosinophils in local tissue. In a