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RNA folding and the origins of catalytic activity in the hairpin ribozyme

✍ Scribed by Timothy J. Wilson; Michelle Nahas; Lisa Araki; Shinya Harusawa; Taekjip Ha; David M.J. Lilley

Book ID: 116304198
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 460 KB
Volume: 38
Category: Article
ISSN: 1079-9796
DOI: 10.1016/j.bcmd.2006.10.004

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## Abstract The hairpin ribozyme is a small catalytic RNA that has been reengineered resulting in a number of variants with extended or even new functions. Thus, manipulation of the hairpin ribozyme structure has allowed for activity control by external effectors, namely oligonucleotides, flavine m