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RNA Flexibility and Folding in Crowded Solutions

โœ Scribed by Kilburn, John D.; Ho Roh, Joon; Guo, Liang; Briber, Robert M.; Woodson, Sarah A.


Book ID
122278181
Publisher
Biophysical Society
Year
2012
Tongue
English
Weight
40 KB
Volume
102
Category
Article
ISSN
0006-3495

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## Abstract Simple theoretical models are presented to illustrate the effects of spatial confinement and macromolecular crowding on the equilibria and rates of protein folding and binding. Confinement is expected to significantly stabilize the folded state, but for crowding only a marginal effect o