RNA editing of sorghum mitochondrialatp6transcripts changes 15 amino acids and generates a carboxy-terminus identical to yeast
✍ Scribed by F. Kempken; J. A. Mullen; D. R. Pring; H. V. Tang
- Book ID
- 104720191
- Publisher
- Springer-Verlag
- Year
- 1991
- Tongue
- English
- Weight
- 975 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0172-8083
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✦ Synopsis
Sequencing of sorghum mitochondrial atp6 cDNA clones revealed 19 C-to-U transcript editing events within a 756 bp-conserved core gene; three were silent and 16 resulted in 15 amino acid changes. Only one edit, which was silent, was found in the 381 bp amino-extension to the core gene. Eleven of the 15 changed amino acids were identical with or else represented conservative changes compared to yeast atp6. Editing of a CAA codon to TAA truncates the carboxy-terminus to a position identical to that of yeast. The frequency of editing at sites which change amino acids was very high in contrast to partial editing at silent, third base, sites.