RNA editing at a splicing site of NADH dehydrogenase subunit IV gene transcript in wheat mitochondria

A novel splice-acceptor site mutation (I

A novel splice-acceptor site mutation (IVS13-2A>T) of polycystic kidney disease 1 (PKD1) gene resulting in an RNA processing defect with a 74-nucleotide deletion in exon 14 of the mRNA transcript

✍ Anna Thongnoppakhun; Nanyawan Rungroj; Prapon Wilairat; Kriengsak Vareesangthip; 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 222 KB 👁 3 views

Autosomal dominant polycystic kidney disease (ADPKD) occurs mainly from mutations of polycystic kidney disease 1 (PKD1) gene. A novel mutation of the PKD1 gene due to a nucleotide substitution in splice-acceptor site of IVS13 (AG->TG) was identified by analyses of PKD1-cDNA and genomic DNA. The IVS1