Non-WatsonαCrick base pairs or mismatches in RNA crystal structures have been summarized and their effects on the geometry of RNA molecules and their biological implications have been discussed. The mismatches can distort the helical structures by producing kinksrbends and can increase or decrease t
RNA Composition and Base Pairing
β Scribed by Traub, W.; Elson, D.
- Book ID
- 121176777
- Publisher
- American Association for the Advancement of Science
- Year
- 1966
- Tongue
- English
- Weight
- 710 KB
- Volume
- 153
- Category
- Article
- ISSN
- 0036-8075
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Second communication in the series 'Pyranosyl-RNA (3-RNA') '; for the first communication (which represented Part VII of the series 'Why Penfose-and Not Hexose-Nucleic Acids?'), see [I]. The present paper is also communication No. 16 in the series 'Chemisfry ofa-Amino Nifnles', for communication No.
The ultraviolet absorption, optical rotat,ory dispersion, circular dichroism, and infrared absorption spectra of renatured 5s RNA have been measured at pH 7.0 in O.1M NaCl at 25" and used to obtain four independent estimates of the number of base pairs. These four estimations are in reasonable agree