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Rituximab therapy for juvenile-onset systemic lupus erythematosus

✍ Scribed by Obioma Nwobi; Carolyn L. Abitbol; Jayanthi Chandar; Wacharee Seeherunvong; Gastón Zilleruelo

Publisher
Springer
Year
2007
Tongue
English
Weight
139 KB
Volume
23
Category
Article
ISSN
0931-041X

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## Abstract ## Objective Accumulation of apoptotic cells may lead to the development of systemic lupus erythematosus (SLE) through a breakdown in immune tolerance. Altered neutrophil apoptosis may contribute to nuclear autoantigen exposure, ultimately leading to autoantibody generation. This study