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Rituximab in the treatment of severe lupus myelopathy

✍ Scribed by Yan Ye; Jie Qian; Yueying Gu; Xiaoqing Chen; Shuang Ye

Book ID
106265975
Publisher
Springer
Year
2011
Tongue
English
Weight
166 KB
Volume
30
Category
Article
ISSN
0770-3198

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## Abstract ## Objective B cells are likely to contribute to the pathogenesis of systemic lupus erythematosus (SLE), and rituximab induces depletion of B cells. The Exploratory Phase II/III SLE Evaluation of Rituximab (EXPLORER) trial tested the efficacy and safety of rituximab versus placebo in p