Risk of kidney cancer among patients using analgesics and diuretics: A population-based cohort study

✍ Scribed by Per Lindblad; Joseph K. McLaughlin; Anders Mellemgaard; Hans-Olov Adami

• Publisher: John Wiley and Sons
• Year: 1993
• Tongue: French
• Weight: 530 KB
• Volume: 55
• Category: Article
• ISSN: 0020-7136
• DOI: 10.1002/ijc.2910550103

✦ Synopsis

The aim of this study was to determine the risk of kidney cancer in 2 cohorts defined on the basis of hospital discharge diagnoses associated with analgesic or diuretic use during the period 1965 to 1983. Patients were followed up through 1984 for cancer incidence. After excluding cancers in the first year of observation, 161 kidney cancers were observed vs. 138 expected among 54,662 patients in the analgesics cohort. The relative risk was higher for women than for men. When examined by sub-site within the kidney, risk for cancer of the renal pelvis was similar in magnitude to that for the renal parenchyma. Among I 15.6 I 6 patients in the diuretics cohort, 278 kidney cancers occurred vs. 209 expected. The risk for