Risk of hepatitis C virus (HCV) transmission by anti-HCV-negative blood components in Austria and Germany
✍ Scribed by J. Riggert; D. W. M. Schwartz; A. Uy; G. Simson; F. Jelinek; H. Fabritz; W. R. Mayr; M. Köhler
- Publisher
- Springer
- Year
- 1996
- Tongue
- English
- Weight
- 567 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0939-5555
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Serum samples from 103 blood donors or patients with slightly increased serum levels of liver enzymes were tested for antibodies to hepatitis C virus (anti-HCV) using second generation tests and for HCV RNA by the polymerase chain reaction (PCR). PCR was in a nested configuration, using primer pairs
## Abstract One hundred twenty‐six mother‐infant couples were studied and 105 exposed babies were monitored for at least 12 months to define the risk of mother‐to‐infant HCV transmission. Infection occurred in 5 out of 76 infants (6.6%) born to 69 viraemic mothers and in none of 29 born to 26 non‐v