The effect of gravidity on maternal serum a-fetoprotein (AFP), unconjugated oestriol (uE,), and human chorionic gonadotrophin (hCG) levels was investigated in 27 592 women being screened for Down's syndrome. There was no difference in the median AFP level in primigravid and multigravid women, but th
Risk of fetal Down's syndrome based on maternal age and varying combinations of maternal serum markers
โ Scribed by I. Bartels; B. Bockel; J. Caesar; M. Krawczak; M. Thiele; R. Rauskolb
- Publisher
- Springer
- Year
- 1994
- Tongue
- English
- Weight
- 549 KB
- Volume
- 255
- Category
- Article
- ISSN
- 0003-9128
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We conducted a study to investigate the effect of parity on the following six serum markers used in screening for Down's syndrome, after adjusting them for ethnic group and maternal weight: alpha-fetoprotein (AFP), unconjugated oestriol (uE,), total human chorionic gonadotrophin (hCG), free a-hCG, f
High free beta human chorionic gonadotropin ( -hCG) and low alpha-fetoprotein (AFP) levels were found in 47 Asian Down's syndrome pregnancies (median values 2โข79 and 0โข77 MOM, respectively). At a 5 per cent false-positive rate, free -hCG alone would identify 46โข8 per cent of Down's syndrome pregnanc
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