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Risk of colorectal neoplasia in patients with primary sclerosing cholangitis and ulcerative colitis following orthotopic liver transplantation

โœ Scribed by Edward V. Loftus Jr.; Humberto I. Aguilar; William J. Sandborn; William J. Tremaine; Ruud A. Krom; Alan R. Zinsmeister; Ivo W. Graziadei; Russell H. Wiesner


Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
71 KB
Volume
27
Category
Article
ISSN
0270-9139

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Between February 26, 1981, and July 30, 1987, 36 patients underwent orthotopic liver transplantation for primary sclerosing cholangitis associated with ulcerative colitis. Three of the 36 recipients died within 3 mo because of graft nonfunction or surgical complications. The other 33 (92%) lived for

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## Background: Controversy persists regarding primary sclerosing cholangitis (psc) as a risk factor for colorectal carcinoma in patients with chronic ulcerative colitis. small sample size and differing endpoints have contributed to variation among reported studies. this large case-control study was