## Abstract Estrogen receptor (ER) status is an important biomarker in defining subtypes of breast cancer differing in antihormonal therapy response, risk factors and prognosis. However, little is known about association of ER status with various risk factors in the developing world. Our caseβcontr
Risk factors and clinical data related to oestrogen receptor status in women presenting with breast cancer
β Scribed by A. C. V. Montgomery; R. A. McClelland; R. A. Skilton; D. Easton; Breast Cancer
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 522 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0007-1323
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β¦ Synopsis
Abstract
Oestrogen receptor (ER) content was measured in 257 patients presenting with βoperableβ breast cancer. Difference in age, menopausal status, parity, age at first pregnancy, breast feeding habit and details of past and family history were compared with oestrogen receptor status. The symptoms and their duration together with the extent of the disease both clinically and pathologically were also compared with receptor status. Association both for increasing age and postmenopausal status was found when oestrogen receptors were present in the primary tumours in significant quantities. No separation between the effect of age and menopausal status on oestrogen receptor status could be distinguished. No relationship was demonstrated between oestrogen receptor status and the other clinical and pathological factors examined.
π SIMILAR VOLUMES
Flow cytometry (FC) analysis including DNA index (ploidy status) and cell kinetics (%S and %S + G2/ M) was done on frozen tissue of the primary lesions of 101 women with node negative (N-) breast cancer who were studied prospectively . Currently, 19% (19/101) of the patients have recurred. No signif