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Ring transformations in reactions of heterocyclic compounds with nucleophiles. The conversion of 5-nitropyrimidine into pyridine derivatives by CH-acitve nitriles

โœ Scribed by Valery N. Charushin Postdoctoral Fellow; Henk C. van der Plas


Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
378 KB
Volume
102
Category
Article
ISSN
0165-0513

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Ring transformations in reactions of het
โœ H.J. den Hertog; R.J. Martens; H.C. van der Plas; J. Bon ๐Ÿ“‚ Article ๐Ÿ“… 1966 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 173 KB

Halogenopyridines and derivatives of these substances react with potassium amide in liquid ammonia according to various patterns. Together with normal substitutions of halogen atoms by the amino group, replacements with ortho-, meta---and para-rearrangements have been observed (2). whereas by nay o