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Ring-Opening of Unsymmetrical 1,2-Dioxines Using Cobalt(II) Salen Complexes.

✍ Scribed by Ben W. Greatrex; Dennis K. Taylor


Publisher
John Wiley and Sons
Year
2005
Weight
34 KB
Volume
36
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

For Abstract see ChemInform Abstract in Full Text.


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Enantioselective Synthesis of Ξ²-Blockers
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## Abstract The synthesis of chirally pure __Ξ²__‐blockers was successfully achieved __via__ hydrolytic kinetic resolution of butyl (Β±)‐4‐(oxiran‐2‐ylmethoxy)benzeneacetate ((Β±)‐**1**) and (Β±)‐4‐(oxiran‐2‐ylmethoxy)benzeneacetonitrile ((Β±)‐**2**) in the presence of bimetallic chiral [Co(salen)]‐type