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Ring expansion of aziridines to piperidines using the aza-wittig rearrangement

✍ Scribed by Iain Coldham; Alan J Collis; Roger J Mould; Richard E Rathmell


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
199 KB
Volume
36
Category
Article
ISSN
0040-4039

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Ring-expansion of an aziridinone to a he
✍ Mashitah M Yusoff; Erach R Talaty πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 French βš– 196 KB

Reaction of 1,3-di-t,'rt-bu~.laziridinonc (la) and similar aziridinones with thiosemicarbazide affords, as one of the products, a compound devoid of sulfur, vie., a substituted Naminoimidazolidinone (3a) by selective cleavage of the acyl-nitrogcn bond. Compound 3a undergoes a novel, acid-catalyzed r