Ring Expansion of 2-(α-Hydroxyalkyl)azetidines: A Synthetic Route to Functionalized Pyrrolidines
✍ Scribed by François Durrat; Monica Vargas Sanchez; François Couty; Gwilherm Evano; Jérôme Marrot
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 409 KB
- Volume
- 2008
- Category
- Article
- ISSN
- 1434-193X
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## Abstract 2‐(1‐Hydroxyalkyl)azetidines react with bis(trichloromethyl) carbonate (BTC) after basic treatment to afford 4‐(2‐chloroethyl)oxazolidinones. The scope of this rearrangement was examined in detail and its efficiency was shown to depend on the class of the reacting alcohol and on the sub
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