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Ring closure reactions with nitriles. II. Formation of pyrrolo[1,2-a] quinazolines and thiazolo[3,2-a] quinazolines

✍ Scribed by Stanley C. Bell; Peter H. L. Wei


Book ID
112121719
Publisher
Journal of Heterocyclic Chemistry
Year
1968
Tongue
English
Weight
396 KB
Volume
5
Category
Article
ISSN
0022-152X

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✍ Michael Gütschow; James C. Powers 📂 Article 📅 2001 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 68 KB

## Abstract A series of 2‐alkylthio‐4‐oxo‐3‐quinazolineacetonitriles **4** and 2‐alkylthio‐4‐oxothieno[3,2‐__d__]pyrimidine‐3‐acetonitriles **8** was prepared. Upon treatment with sodium hydride, compounds **4** and **8** react to give 2‐amino‐4,9‐dihydro‐9‐oxopyrrolo[2,1‐__b__]quinazoline‐1‐carbon