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Rimonabant reduces keratinocyte viability by induction of apoptosis and exerts topical anti-inflammatory activity in mice

✍ Scribed by Anna Maria Malfitano; Silvio Sosa; Chiara Laezza; Marco De Bortoli; Aurelia Tubaro; Maurizio Bifulco


Book ID
111219726
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
824 KB
Volume
162
Category
Article
ISSN
0007-1188

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## Abstract Methyl 2‐cyano‐3,11‐dioxo‐18β‐olean‐1,12‐dien‐30‐oate (CDODA‐Me) is a synthetic triterpenoid derived from glycyrrhetinic acid, a bioactive phytochemical in licorice, CDODA‐Me inhibits growth of Panc1 and Panc28 pancreatic cancer cell lines and activates peroxisome proliferator‐activated