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Riluzole restores motor activity in rats with post-traumatic peripheral neuropathy

✍ Scribed by M. Medico; A. Nicosia; M. Grech; M. Onesta; G. Sessa; L. Rampello; F. Drago


Book ID
116766404
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
149 KB
Volume
358
Category
Article
ISSN
0304-3940

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## Abstract Patients with hepatic encephalopathy show altered motor function, psychomotor slowing, and hypokinesia, which are reproduced in rats with portacaval shunts (PCS). Increased extracellular glutamate in substantia nigra pars reticulata (SNr) is responsible for hypokinesia in PCS rats. The