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RIG-I Detects Viral Genomic RNA during Negative-Strand RNA Virus Infection

✍ Scribed by Jan Rehwinkel; Choon Ping Tan; Delphine Goubau; Oliver Schulz; Andreas Pichlmair; Katja Bier; Nicole Robb; Frank Vreede; Wendy Barclay; Ervin Fodor; Caetano Reis e Sousa


Book ID
116354279
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
633 KB
Volume
140
Category
Article
ISSN
0092-8674

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## Abstract Hepatitis E virus (HEV), the causative agent of enteric non‐A, non‐B hepatitis, is a positive‐stranded RNA virus. Because of the virus's inability to grow in culture, several nonhuman primates have been used for the propagation of HEV. Using strand‐specific reverse transcription‐polymer