Ribozyme self-replication?
โ Scribed by Cech, Thomas R.
- Book ID
- 109759151
- Publisher
- Nature Publishing Group
- Year
- 1989
- Tongue
- English
- Weight
- 269 KB
- Volume
- 339
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/339507a0
No coin nor oath required. For personal study only.
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The origin of translation has stimulated much discussion since the basic processes involved were deciphered during the 1960s and 1970s. One strand of thought suggested that the process originated from RNA replication in the RNA world (Weiner & Maizels, 1987, 1994). In this paper I seek to extend thi
RNA molecules that are assembled from the four standard nucleotides contain a limited number of chemical functional groups, a characteristic that is generally thought to restrict the potential for catalysis by ribozymes. Although polypeptides carry a wider range of functional groups, many contempora