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Ribozyme-mediated inhibition of caspase-3 activity reduces apoptosis induced by 6-hydroxydopamine in PC12 cells

โœ Scribed by Ren-Huan Xu; Jing Liu; Xian-Wen Chen; Feng Xu; Qing Xie; Hong Yu; Qing Guo; Xia-Qiu Zhou; You-Xin Jin


Book ID
113996906
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
775 KB
Volume
899
Category
Article
ISSN
0006-8993

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Involvement of caspase-like proteinases
โœ Nobuhiko Takai; Hiroshi Nakanishi; Kazunari Tanabe; Tsuyoshi Nishioku; Toshihiro ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 234 KB ๐Ÿ‘ 2 views

Activation of proteolytic enzymes, including the caspase family of proteinases, is a feature characteristic of the apoptotic program. In the present study, we examined a potential role of intracellular proteinases in the death of neuronal PC12 and primary cultured rat microglial cells induced by 6-h